Research Advances in Traditional Chinese Medicine for the Treatment of Recurrent Aphthous Stomatitis
Vol. 28 (2026): 2026 2nd International Conference on Agricultural Sciences, Economics, Biomedical and Environmental Sciences (SEMBE 2026)
Received: 2026-07-18
Accepted: 2026-07-18
Published: 2026-07-18
Abstract
Recurrent aphthous stomatitis (RAS) is a prevalent and frequently recurring oral mucosal disorder characterized by painful ulcerations that significantly impair patients' quality of life. Although modern medicine has associated RAS with multiple contributing factors, including immune dysfunction, genetic predisposition, nutritional deficiencies, and psychological stress, its precise pathogenesis remains incompletely elucidated. Traditional Chinese Medicine (TCM) conceptualizes RAS as a consequence of yin-yang imbalance and dysfunction of the Zang-Fu organs, with the core pathological mechanism involving heat accumulation in the heart and spleen, as well as a complex interplay of deficiency and excess patterns. From the theoretical framework of TCM, this review systematically examines the etiology and pathogenesis, syndrome differentiation, and therapeutic approaches for RAS, encompassing oral herbal administration, topical external applications, acupuncture interventions, and dietary therapy. Additionally, recent advances in novel TCM drug delivery systems are briefly discussed. TCM demonstrates notable strengths in individualized treatment strategies and holistic therapeutic adjustment; however, it continues to encounter challenges regarding the standardization of syndrome differentiation protocols and the objective evaluation of clinical efficacy. Future research should prioritize integrative collaboration between TCM and Western medicine, alongside strengthened basic scientific investigations, to establish a robust evidence base for optimizing clinical diagnostic and therapeutic strategies for RAS.
Keywords
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Published in2026-07-18 11:26:33
DOI https://doi.org/10.70088/9j7s0909
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Journal Information
- Vol. 28 (2026): 2026 2nd International Conference on Agricultural Sciences, Economics, Biomedical and Environmental Sciences (SEMBE 2026)
- 2026-07-18
- ISSN: (Print) 3078-770X/ (Online) 3078-7718
- Journal Homepage